Journal of Practical Hepatology ›› 2023, Vol. 26 ›› Issue (5): 738-741.doi: 10.3969/j.issn.1672-5069.2023.05.034

• Liver transplantation • Previous Articles     Next Articles

Early post-operational complications in patients with orthotopic liver transplantation receiving different deceased donors

Zhang Shugeng, Zhang Shaobo, Zhu Zebin, et al   

  1. Centre of Hepatobiliary Surgery and Organ Transplantation, Anhui Provincial Hospital, First Affiliated Hospital, University of Science and Technology of China, HeFei 230036, Anhui Province, China
  • Received:2023-06-06 Online:2023-09-10 Published:2023-09-13

Abstract: Objective The aim of this study was to investigate the incidences of early post-operational complications in patients with orthotopic liver transplantation (OLT) receiving different deceased donors. Methods 60 patients with end-stage liver diseases were encountered in our center between April 2017 to December 2020, and all underwent allogeneic classical OLT, receiving donation after brain death (BDB) in 27 cases, donation after cardiac death (DCD) in 26 cases and donation after brain death followed by cardiac death (DBCD) in 7 cases. The early (less than 1 month) postoperative complications was defined according to Clavien-Dindo classification, and the incidences of grade III and the above complications were compared among the three groups. Results Out of the 60 patients after OLT, the early postoperative complications of grade III or above occurred in 16 cases (26.6%), and in the grade III complications, there were 2 cases (7.4%) in DBD group, 2 cases (7.7%) in DCD group and 2 cases (28.6%) in DBCD group; as for the grade IV complications, there were 1 case (3.7%) in DBD group, 2 cases (7.7%) in DCD group, and no cases (0.0%) in DBCD group; in the grade V (death) complications, there were 3 cases (11.1%) in DBD group, 3 cases (11.5%) in DCD group, and 1 case (14.3%) in DBCD group, no significant differences as respect to the incidences of complications among the three groups (P>0.05). Conclusion Compared with the standard DBD donor liver, the patients receiving liver from DCD donor or from DBCD donor do not increase the incidence of early postoperative complications.

Key words: Orthotopic liver transplantation, End-stage liver disease, Surgical complications, Deceased donors, Clavien-Dindo classification, Therapy