Abstract: Objective The aim of this study was to summarize the clinical features of patients with portal hypertension and gastroesophageal varices (GOV) under 30 year old of age.Methods The clinical data of 61 inpatients with GOV aged under 30 year old encountered between January 2015 and December 2020 were retrospectively summarized. Results Out of the 61 patients with GOV, the cirrhotic portal hypertension were found in 27 patients (44.3%), including cryptogenic cirrhosis in 11 patients (40.7%), and hepatitis B cirrhosis in 9 patients (33.3%), and noncirrhotic portal hypertension (NCPH) were found in 34 cases (55.7%), including cavernous transformation of portal vein in 21 patients (61.8%); as for the LDRf classification, the varices in our series were mainly Le/ g type, accounting for 77.1%, in terms of diameter, D1.0 for 41.0%, and in terms of bleeding risk factor, the Rf grade 1 were more common (77.1%); the secondary prevention was the main treatment (85.7%), and tissue glue and sclerosing agent injection or band ligation combination was commonly administered (66.1%) in our series; the incidence of rebleeding in patient with NCPH was 11.8%, significantly lower than 29.6% in patients with liver cirrhosis (P＜0.01). Conclusion The majority of young patients with GOV have portal hypertension caused by non-cirrhotic factors, and portal cavernous transformation is the main cause of NCPH. The rebleeding of esophageal and gastric varices in patients with NCPH is relatively lower than that in patients with liver cirrhosis.

Key words: Liver cirrhosis, Non-cirrhotic portal hypertension, Portal hypertension, Gastroesophageal varices