Journal of Practical Hepatology ›› 2021, Vol. 24 ›› Issue (3): 453-456.doi: 10.3969/j.issn.1672-5069.2021.03.038

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Current therapeutic strategy for patients with primary biliary cholangitis

Zhang Xinhe, Tian Haoyu, Li Yiling   

  1. Department of Gastroenterology, First Affiliated Hospital,China Medical University, Shenyang 110001, Liaoning Province, China
  • Received:2020-03-19 Online:2021-05-30 Published:2021-04-30

Abstract: Primary biliary cholangitis (PBC) is a chronic, progressive, non-suppurative inflammation of the small bile ducts in the liver. Ursodeoxycholic acid is the only first-line therapeutic drug at present. New progress has been made in the research on the efficacy of second-line drugs such as obieticholic acid, betts and immunosuppressants. The efficacy and safety of non-drug intervened measure are under investigation. There are also different treatment ways for different extrahepatic manifestations of patients with PBC. In this review, we put focus on the current progress of treatment for PBC patients.

Key words: Primary biliary cholangitis, Ursodeoxycholic acid, Obieticholic acid, Therapy