关键词: 肝脏局灶性病变, 钆塞酸二钠, 磁共振成像, 计算机体层扫描, 诊断

Abstract: Objective To investigate the efficacy of gadolinium disodium enhanced MR in the diagnosis of patients with focal liver lesions（FLL）. Methods 47 consecutive patients with FLL were selected in our hospital between June 2015 and June 2017. The liver biopsies were performed and the diagnoses were confirmed by histopathology. All patients underwent disodium gadoxate enhanced MR with or without hepatobiliary phase,and enhanced CT scan. The independent blind analysis was performed by radiologists based on the five-point scale. Results The lesion size was 0.7~6.2 cm（2.1±0.8） cm in the 47 patients with FLL,and the pathological examination demonstrated cholangiocarcinoma in 15,biliary cystadenocarcinoma in 1,metastases from colorectal cancer in 11,and hepatic hemagioma in 5,hepatic focal nodular hyperplasia in 8,nodule with underlying liver cirrhosis in 4,lipoma in 2 and adenoma in 1;the sensitivity,specificity and accuracy by MRI with hepatobiliary phase scan were 88.9%,80.0%and 85.1%,much higher than 60.0%,61.7% and 63.0% by MRI without hepatobiliary phase scan or 45.0%,48.9% and 51.9% by CT scan,respectively（P<0.05）. Conclusion The application of gadolinium-disulfonate-enhanced MR scan is beneficial for the qualitative diagnosis of patients with FLL,which warrants further investigation.

Key words: Focal Liver lesions, Gadistelate disodium, MR, CT, Diagnosis